Posts Tagged ‘stress’
The anti-inflammatory drugs to treat depression?
The death of nerve cells caused by stress was blocked by anti-inflammatory molecule in a study published in the Proceedings of the National Academy of Sciences. This suggests that one way to treat certain symptoms of depression and stress could reduce the activity of the immune system that causes inflammation.
The idea that some cases of depression could be caused by an inflammatory response has gained prominence over the last decade, from a clinical trial of an anti-inflammatory drug for psoriasis had an antidepressant side effects unexpected.
Previous research has suggested that cytokines block the birth of new neurons (nerve cells) in the hippocampi of stressed and depressed, an effect that may underlie some symptoms of depression such as memory problems.
Ronald Duman and his colleagues at Yale University studied the cytokine NF-kB is known to control several immune responses, to see if its release could reduce neurogenesis (the creation of new neurons) and whether these effects could be prevented .
After stress, whether acute or chronic, there were fewer neurons created in the brain of rodents. When they received an inhibitor of NF-kB before the stress, the birth of new neurons continued at a normal rate.
Duman hopes that a cytokine inhibitor can be developed as a treatment option for people with depression who do not respond to conventional treatment with antidepressants. “Depression is not a single disease,” he said. “A sub-group of depressed people may have an inflammatory condition, while other sub-groups could be better treated with existing antidepressant medications.”
While other anti-inflammatory drugs are in clinical trials for the treatment of depression, Tad Pace of Emory University, who studies the immune system function in people with major depression, said that NF -kB might be a better target for a drug because it is the first of a signaling cascade involving several other citokines.
Joe Herbert of Cambridge University, who studies the factors that affect neurogenesis, warns of possible complications with this type of treatment. “Developing drugs that interfere with the cytokine NF-kB can be problematic given its widespread function in the organization and its involvement in the development of cancer.
Pace remains optimistic, hoping to see the anti-inflammatory drugs, such as an inhibitor of NF-kB, regularly prescribed for the treatment of depression in the next 10 years.
Posted in Mental Health | 
Tags: depression, Mental Health, stress, Symptoms of depression | 
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Benefits of Chewing Gum
I must confess: I have just one addiction and is chewing gum all the time. No matter where or when, nor whether it is appropriate or not, I really like chewing gum … and I do always.
That’s why we read this news made me super happy, because I knew that with my “addiction” I was doing really well. Apparently chewing sugarless gum increases blood flow to the brain, increases the supply of oxygen that activates the alert and consequently improves concentration.
Posted in Healthy Tips | Tags: Benefits of Chewing Gum, Chewing gum, gum, stress, sugarless gum | No Comments »
Causes of Premature Ejaculation
“Premature ejaculation is feared by men and women suffered” as well as catalogs the American sexologist Clarise Mourron, Institute for the treatment of premature ejaculation in Arizona.
There are several definitions to describe this disease that affects nearly 40% of men, but basically it is a dysfunction or a series of sexual dysfunction often or very often makes a man can not control ejaculation.
A couple of years was common to early ejaculatory try the man who could not bear “X” number of pelvis movement without ejaculating, but that theory was abandoned as there are many ways that interfere with male ejaculation and the environment social, work, family problems, age, stress, etc..